The first beta of the reference manager Zotero 3.0 was released (https://web.archive.org/web/20120525045252/http://www.zotero.org/blog/announcing-zotero-3-0-beta-release/?) yesterday. The big news is that Zotero 3.0 no longer only runs within the Firefox browser, but is now also available as a standalone version similar to other reference managers.
Zotero Connectors integrate with the Chrome and Safari browser. They also allow saving directly to your Zotero library at zotero.org.
Zotero does not support Internet Explorer. Users of this blog are not representative of all internet users, and Zotero 3.0 would offer browser support for more than 80% of them.
Zotero 3.0 is beta software and you should expect bugs. One small problem I discovered is that the German translation is incomplete, e.g. in the menus. But overall Zotero looks and feels very similar to the familiar Zotero 2.1 – just as a standalone version. One new feature I like is duplicate detection, an experimental feature of earlier versions.